Mathematical Modelling of Post-Transcriptional Regulation of Gene Expression

To make protein, information in the gene is copied through transcription, producing messenger-RNA (mRNA). However, the mRNA might bind to an RNA-induced silencing complex (RISC), preventing the information in the mRNA being translated into the protein. A RISC consists of micro-RNA bound to protein Argonaute. The project develops mathematical models based on differential equations on how the concentrations of RISC and Argonaute, as well as the rate of binding rates, affect the rate of protein synthesis.

Eunice Blessica Yuwono

The University of Adelaide

Eunice is in her second year of a Bachelor of Mathematical Sciences (Advanced) at The University of Adelaide. After graduating high school with satisfactory Cambridge International A Level results in Indonesia, she went to Adelaide to pursue her passion in using Mathematics to solve real world problems. Her interest is in modelling vast range of issues, from Biology to Music, using Mathematics. Her past work involves creating a stochastic model of a song. She volunteered as a teaching assistant in her high school during summer break and tutors privately during her studies in Adelaide.

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