Fixing Sore Knees: Mechanics of Artificial Cartilage

A previous work has modelled focusing on examining the role of different TGF-beta concentrations and the initial cell seeding straties. This project will extend that earlier work by including the role of mechanical stimulation. This will involve incorporating for the 􀂦rst time the full biomechanics of TGF-β activation. This will require a model of the cell biology to be coupled with a model of the mechanical behaviour of the hydrogel culture medium when subjected to mechanical stimulation (strain). If time permits, the potential for chondrocytes to remodel their environment by the secretion of collagen (and other substances) will also be investigated with a view to recreating the zonated structure of natural cartilage.

Lin Jiang

The University of Adelaide

Lin Jiang is an undergraduate international student in The University of Adelaide, undertaking a double degree programme of Bachelor Chemical Engineering and Mathematics. During her study life, she focused more in conducting researches about investigating the industrial unit operation, and have received high efficient learning skills. She also gained a great communication skills from a few work experiences such as being a consultant for making an investment or analysis for different people’s inquires working in a team.

After the university, she also has many volunteering works to learn a different culture, such as looking after some homeless cats in Cafinc organisation until they have been adopted. She also has a part-time job of making cakes in the dessert shop. Her long-term goal is to become a real researcher to develop a better scope for the undiscovered field.

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